Searchable abstracts of presentations at key conferences in endocrinology

ea0077op3.4 | Reproductive and Neuroendocrinology | SFEBES2021

Stem cell heterogeneity and regulation in the postnatal pituitary gland

Willis Thea L. , Yianni Val , Santambrogio Alice , Russell John P , Lodge Emily , Charalambous Marika , Andoniadou Cynthia L.

The anterior pituitary gland is a critical endocrine organ responsible for many important physiological processes including puberty, fertility, metabolism and the stress response. It is derived from, and maintained by, a population of SOX2+ progenitor/stem cells which become more quiescent with age until their direct contribution to tissue turnover becomes negligible. Previous research has demonstrated that the postnatal SOX2+ population exhibits heterogeneity in terms of mark...